http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2789348-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f218ced6ba06e24bfaa38739487aa2d |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate | 2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99f15c1902cf4578fab51da4d56e0efa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae29f84199c8cc549a41c99b9cef3498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ef342272dfb5bca94a0d988da7b7923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb169b037e2f4917a862819832543ecb |
publicationDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2789348-A2 |
titleOfInvention | Liposomes and corresponding production method |
abstract | The present invention is the use of conjugated peptide sequences for inclusion in liposomal membranes. The combination can be done with folic acid or with an antibody of folic acid receptor coupled to N-terminal peptide. The presence of these peptides conjugated to liposomal formulations allows the targeting and subsequent release of therapeutic agents and / or imaging agents to cells expressing folic acid receptor. n The developed method combines the ability of liposomes in the transport and release of drugs and the specific expression of folic acid receptor on the surface of cell membranes that allow transmembrane transport mediated by specific liposomes. Thus allows the transport of therapeutic agents and / or imaging agents, which are inside the liposome, either hydrophobic or hydrophilic. The therapeutic agents can be either pharmacological compounds (active agents) or siRNAs (small interference RNA) specific to defined target genes. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017105344-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108430457-A |
priorityDate | 2011-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.