| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1dae008baa5e165bff1b8a6178aafa7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5767
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-576
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-576 |
| filingDate |
2012-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44cdc7848b339ae7a5f37444973083ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc8d007d2ee71ba2d51b49aad63ce9b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3aea74ad22a1656553c7b95af0f62d |
| publicationDate |
2014-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2785876-A1 |
| titleOfInvention |
Methods for the phenotypic detection of hcv inhibitor resistant subpopulations |
| abstract |
Methods and compositions for the efficient and accurate determination of MIsceptibility of a hepatitis C virus (HCV) population to an HCV inhibitor are provided. In certain aspects, the methods involve introducing into a cell a patient derived segment, wherein the cell or the patient derived segment comprises an indicator nucleic acid that produces a detectable signal that is dependent on the HCV; measuring the expression of the indicator gene in the presence of varying concentn'ltions of the HCV inhibitor: determining a standard curve of susceptibility: comparing the IC95 fold change, slope, or maximum inhibition percentage of the HCV population to that of a control HCV population |
| priorityDate |
2011-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |