http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2771467-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49310188df8dc04b3708491df863459f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8218 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8269 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y306-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y401-01031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-415 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 |
| filingDate | 2012-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a13f77fc8f4408e1fe10f3365aa77c66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e5fbd0622ad79d19c3edc08fdf13822 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ec43daf872e93141a696e0a04bb98dd |
| publicationDate | 2014-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2771467-A1 |
| titleOfInvention | Methods and compositions for silencing genes using artificial micrornas |
| abstract | Methods and compositions are provided that employ microRNA (miRNA) that, when expressed in a plant cell, is capable of reducing the level of mRNA of a target sequence (i.e. endogenous sequence) without reducing the level of mRNA of one or more closely related sequences. While miRNAs can be designed with specificity for a particular target sequence, the instant application demonstrates that a miRNA can specifically silence a target sequence without silencing a closely related sequence having high sequence identity to the target sequence. In certain embodiments, an endogenous target sequence can be suppressed with a recombinant miRNA expression construct without silencing a recombinant polynucleotide of interest having a sequence closely related to the target sequence. Such methods and compositions employ recombinant miRNA expression constructs which produce a 21-nt miRNA. Transgenic plant cells, plants and seeds incorporating miRNA expression constructs and recombinant polynucleotide constructs comprising polynucleotides of interest are also provided. |
| priorityDate | 2011-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 665.