| abstract |
The present application relates to novel substituted 5-(1,2,4-oxadiazolo-5-yl) pyridine-2-ones and 6-(1,2,4-oxadiazolo-5-yl) pyridazine-3-ones, a method for preparation thereof, the use thereof for treatment and/or prevention of diseases, and for producing medicines for the treatment and/or prevention of diseases, in particular for treating and/or preventing hyperproliferative and angiogenic disorders, and disorders that are caused by a metabolic adaptation to hypoxic conditions. Such treatments can be carried out as monotherapy or in combination with other medicines or additional therapeutic measures. |