http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2755690-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 |
| filingDate | 2012-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a331ea51d9948b5ffa20f17d9542f26d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_978a93e329ba291be869fdfc131c4e90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2071e2e13013265519e9dad35230c2e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ff16aafc1197a1b2a2c28536e180932 |
| publicationDate | 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2755690-A1 |
| titleOfInvention | Kisspeptide-pentasaccharide conjugates |
| abstract | The invention relates to kisspeptide-pentasaccharide conjugates having the general formula (I) wherein Ζ 1 is Tyr or D-Tyr; Z 3 is Trp, Hyp, Phe or Lys(R 2 ); Z 5 is Thr, Aib or Ala; Z 7 is Gly or azaGly; Z 8 is Leu; or Z 7 and Z 8 together represent; Z 10 is Phe or Trp; n is 0 or 1; or R 2 , when present, represents a pentasaccharide derivative having the formula (II) wherein R is methyl or SO 3 X; X is a positively charged counterion; with the proviso that when R 2 is present, R 1 is H or (C 1-6 ) alkylcarbonyl; R 3 is H or (C 1-3 )alkyl; and L represents a pharmacologically inactive linker moiety having 10-50 atoms; or a pharmaceutically acceptable salt thereof; to pharmaceutical compositions comprising the same as well as to the use of said kisspeptide-pentasaccharide conjugates in the treatment of female infertility. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2571896-C2 |
| priorityDate | 2011-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 400.