| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25c4fc4e202922a16436d7d118f2043e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad47638fd0c6f06423c12110871a44dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c0f16accb48d5c8ed3c62caa4321b95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e30efc4af5b19b9807ffefe10bf69cf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac016af4a92483258f40d034f76ba15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f636b94955662fcecbc93bced23d6a1d |
| publicationDate |
2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2748200-A1 |
| titleOfInvention |
Fc-free antibodies comprising two fab fragments and methods of use |
| abstract |
The present invention relates to bispecific antibodies comprising at least two fab fragments, wherein the first Fab fragment comprises at least one antigen binding site specific for a first antigen; and the second Fab fragment comprises at least one antigen binding site specific for a second antigen,wherein either the variable regions or the constant regions of the second Fab heavy and light chain are exchanged; and wherein the bispecific antibody is devoid of a Fc domain; methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. |
| priorityDate |
2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |