| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41a639aa11b9b2f8063a3e6b8b22b557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_700ff9a01db2075489cb7ed87392dc28 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 |
| filingDate |
2012-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cfa4f77bcdf16d5660a376220da8294
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58cd66d852108656f508a3e0d2b1f4d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc75070b74fd1c1861b0d815663b5e69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6846dca7bebfe668a467d0f7c85b4b07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dfd17f55335d3a3d3850f918fe02056 |
| publicationDate |
2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2748193-A1 |
| titleOfInvention |
Method for reducing the thromboembolic potential of a plasma-derived immunoglobulin composition |
| abstract |
The present invention provides methods for reducing the amidolytic and anti-complement activity (ACA) content of an immunoglobulin composition through the use of cation exchange chromatography. In a specific embodiment, the invention provides methods for reducing the Factor XI and/or Factor XIa and/or ACA content of an immunoglobulin composition by collecting the leading portion of a cation exchange eluate. The present invention also provides immunoglobulin composition having reduced levels of amidolytic activity, Factor XI, and/or Factor XIa, and/or ACA content. |
| priorityDate |
2011-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |