| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_412e636b4b40a474c79acb8fd9a56331 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F251-00 |
| filingDate |
2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f46d613a147df0cc9ab789f4394bb20b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1783e56d19e3c1118ab99edd4537caef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95495a44aaba8738cfe3ae0575df5748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40197a7eb1df117eabe7a416a55c7437
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d1e47df51c83ca4b7f201e63bf02885
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fa32ce1b6c4cd3517bef575370ef493 |
| publicationDate |
2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2734557-A1 |
| titleOfInvention |
Production of thermoreversible hydrogels for therapeutic applications |
| abstract |
A method is disclosed for production of a sterile thermoreversible hydrogel characterized by a known temperature T min at which the viscosity reaches at least a local minimum. In a preferred embodiment of the invention, the method comprises dissolving the components in water within ± 4 °C of T min ; forming the thermoreversible hydrogel; and filtering the thermoreversible hydrogel at T min . The final sterilization can be obtained by filtering under aseptic conditions or by autoclaving or irradiation of the final product. In other embodiments, the components of the gel are dissolved in a sufficiently large quantity of water that reduces the gel viscosity or precludes formation of a thermoreversible hydrogel, and sufficient water is then removed under vacuum to produce the final thermoreversible hydrogel. |
| priorityDate |
2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |