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filingDate 2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b51a1b67d61830c914cbac89e2ee2b79
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publicationDate 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2734215-A1
titleOfInvention Improved process for pygeum extraction
abstract An improved process for the extraction of pygeum from the plant of the family rosacaea, amygdales tribe, genus Prunus species domestica ( Indian Prunus ) and related species (as herein defined) comprising the steps of collecting the plant material i.e. stem cuttings/ twigs, removing the leaves and drying till moisture content is about 10-15%, powdering the stem material, extracting with chlorinated organic solvents and water-alcohol mixture, in ratio of 1 :4, filtering and drying the extract under vacuum at 30 degree Celsius to obtain a greenish mass with bitter almond smell, the mass being referred to as 'pygeum' wherein in the improved process, a 'renewable plant source' i.e. stem cuttings/ twigs, are used for extraction of pygeum instead of a 'non-renewable' source such as bark of the tree. The pygeum obtained by the new process has a pharmacopeia profile similar to the product 'pygeum' obtained from a 'non- renewable source' i.e. bark of Pygeum africanum . Further, it is non-toxic and shows anti-BPH (benign prostatic hyperplasia) activity comparable with that of pygeum obtained from non-renewable source i.e. bark of Prunus Africana .
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