| abstract |
The present invention relates to a method for the in vitro diagnosis of active tuberculosis, comprising a step of contacting lymphocytes of a patient suspected to have active tuberculosis with at least one protein of mycobacteria, said protein being an enzyme having a lipolytic activity (eg a monoacylglycerol hydrolase such as Rv0183, a phospholipase such as Rv3452, Rv3802c, PlcA, PlcB, PlcC or PlcD, the lipase Rv1984c, or a triacylglycerol hydrolase, such as LipY), and a step of detecting the presence of specific activated lymphocytes. |