http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2708891-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbe675b46d686407d64e31a937562663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d65b0d354849084d528a3434f470fd44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9e1dbfee18d681ba7221759b01afc95 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2012-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_329e9d4be49b1e5687c6db4796235a76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_284ef270832d7ab7cdb5032db5b6b4c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45471b3c3019eda28df7a980990fe5ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72993be08fbf78ed0fa932b11b507512 |
| publicationDate | 2014-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2708891-A1 |
| titleOfInvention | In vitro method for determining immunotoxicity of a compound |
| abstract | The invention is in the field of molecular diagnostics. More in particular it provides marker genes for determining the immunotoxicity of compounds. A method according to the invention employs samples obtained from a cell exposed to a potentially immunotoxic compound and determines expression levels of a number of marker genes in order to distinguish between immunotoxic compounds and non-immunotoxic compounds. More in particular, the invention relates to an in vitro method for determining whether a compound is immunotoxic wherein the expression level of at least one marker gene is determined in a sample obtained from a nucleated cell exposed to the compound, wherein the at least one marker gene is selected from the group consisting of ABCA1, CHAC1, CRIM1 and HMGCS1, and wherein it is concluded that the compound is immunotoxic if the expression level of said at least one marker gene is below or above a predetermined reference value. |
| priorityDate | 2012-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.