http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2706121-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_487f95154be3da3497db1e7dcb4fdeb0 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-924 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-66 |
filingDate | 2009-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2277d5e14e5423ac3430457bc53be725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae6c13d0c364b6deef8f1c9f512cc05d |
publicationDate | 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2706121-A1 |
titleOfInvention | Enzymatic substrate building blocks for multiple detection systems |
abstract | An inventive substrate is provided which includes a substrate compound of formula A-B 1 -B 2 -B 3 -B 4 : wherein A is a sugar moiety; B 1 is a linker moiety allowing the conjugation of moiety A and the remaining structure of the substrate; B 2 is a linker moiety with a free reactive amino group so as to be available for reaction with carboxylic acids or detectable tags; B 3 contains a permanently charged element such as a quaternary ammonium group so as to increase sensitivity for mass spectrometry analysis; and B 4 of various carbon length conferring specificity amongst individual substrates in detection methods. Also provided is a molecule of the formula B 1 -B 2 -B 3 -B 4 , with similar structural characteristics to an enzymatic product produced by the action of a target enzyme on an inventive substrate. Further provided are methods for using inventive substrates for detecting enzymatic activity. |
priorityDate | 2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 248.