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filingDate 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_770701de6c47602f0b2981ba2552818a
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publicationDate 2014-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2692368-A1
titleOfInvention Biodegradable particle, vascular embolization material and method for producing biodegradable particles
abstract The present invention aims to provide a biodegradable vascular embolization material that is less likely to coagulate and has an improved flexibility, and whose particle shape is recovered after its passing through a catheter or the like. The present invention provides a biodegradable particle comprising a block copolymer produced by copolymerization of: a biodegradable copolymer having a structure composed of hydroxycarboxylic acid a1, whose homopolymer produced by homopolymerization has a glass transition point of not less than 40°C, and hydroxycarboxylic acid a2, whose homopolymer produced by homopolymerization has a glass transition point of not more than -40°C; a water-soluble polymer comprising a functional group selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group at each of both ends; and a polyvalent compound comprising 2 or more functional groups each selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group; wherein the ratio of the mass of the structure composed of hydroxycarboxylic acid a2 to the mass of the biodegradable copolymer is 30 to 90% by mass.
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