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publicationDate 2014-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2682775-A1
titleOfInvention Field Cycling Method for Magnetic Resonance
abstract An NMR experiment on hyperpolarizable magnetic nuclei of substrate molecules in a living human or animal body, with: na) the substrate molecules are polarized by non-hydrogenating para-hydrogen induced polarization (=NH-PHIP) into a singlet/pseudo singlet state in low magnetic field ; nb) the substrate molecules are injected into the living body, wherein said body or a part thereof is already located inside a magnet at low magnetic field; nc) the magnet is switched on to high magnetic field, and in at least part of the substrate molecules, the singlet state/pseudo singlet state is converted into observable magnetisation; nd) an MRI or MRS measurement is carried out with the living body or the part thereof, collecting data from the substrate molecules. n The NMR experiment is well applicable on hyperpolarized nuclei within a patient, with reduced losses of magnetization due to relaxation processes.
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