http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2675790-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-20 |
filingDate | 2012-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f09e559101be780019c0ad845addbfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2f17623cc36449239d1427382b9287a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8dc4f9a9d980d3547db0eff280b7584 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09017fe74bc5d241676ce0e4259da63e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c82cd738179a0f9b028432450a9d2a1 |
publicationDate | 2013-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2675790-A1 |
titleOfInvention | Substituted 1, 2, 3, 4-tetrahydroquinolin-7-yl carbamates as acetylcholinesterase inhibitors for treatment of alzheimer's disease |
abstract | The present invention relates to novel substituted l,2,3,4-tetrahydroquinolin-7-yl carbamates, their preparation, and use as therapeutic agents, particularly in the prevention or treatment of neurodegenerative or Alzheimer's disease, or senile dementia, or memory disturbances, and more particularly to the prevention, treatment and amelioration of Alzheimer's disease with the novel substituted l,2,3,4-tetrahydroquinolin-7-yl carbamates, which act as inhibitors of central cholinesterase enzymes, particularly acetylcholinesterase (AChE) following the indirect cholinomimetic pathway. The present invention particularly relates to compounds of formula A: Formula A wherein Ri = alkyl, aryl, substituted aryl; R2 = H, methyl; R3 = H, alkyl, alkenyl, alkynyl, aralkyl, substituted aralkyl, aryl, heteroaryl. |
priorityDate | 2011-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 399.