| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2817954cd008bcd609a4c4eb49050be |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90666
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2012-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adc5738a410cc041a6d18020e98be8a8 |
| publicationDate |
2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2667196-A1 |
| titleOfInvention |
Bioorthogonal chemical inducers of reversible dimerization for control of protein interactions in cells |
| abstract |
The present application refers to bioorthogonal chemical inducers of reversible dimerization for control of protein interactions in cells. A compound, a test system, methods and uses are disclosed how the invention can be applied in the investigation of intracellular protein interactions. The system is composed of SLF'-TMP as the dimerizer, displaying a high affinity binding to FKBP(F36V) mutant and eDHFR, respectively. The system is reversible on addition of TMP. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3424922-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019008175-A1 |
| priorityDate |
2012-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |