http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2662367-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a98cb1b197f761c87cd3caf32bc247e2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 |
filingDate | 2012-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b53b8062794b1011f166b8d17dd50226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0733009f8f9a5ca1a98ec67cc0a81a8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0de59d9e092d48dbac7dd7bbc7f0457 |
publicationDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2662367-A1 |
titleOfInvention | Novel indole or indazole derivative or salt thereof |
abstract | The the present invention relates to provision of a novel indazole compound which is capable of inhibiting HSP90 and shows a cytostatic effect on cancer cells. The present invention also relates to provision of a drug useful for preventing and/or treating, on the basis of an HSP90 inhibitory effect, a disease in which HSP90 participates, in particular, cancer. A compound represented by the general formula (I) or a salt thereof:n nwherein nX represents CH or N; nany one or two of Y 1 , Y 2 , Y 3 , and Y 4 represent C-R 3 or N, and the others represent CH; nA and B are the same or different and represent an optionally substituted monocyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S, and O; nR 1 represents a hydrogen atom, an optionally substituted alkyl group having 1 to 6 carbon atoms etc.; nR 2 represents a hydrogen atom, a halogen atom etc.; nR 3 represents a hydrogen atom, a halogen atom etc.; nR 4 and R 5 are the same or different and represent a hydroxyl group etc.; nR 6 and R 7 are the same or different and represent a hydrogen atom, an alkyl group having 1 to 6 carbon atoms etc.; and nR 8 represents an optionally substituted cycloalkyl group having 3 to 7 carbon atoms etc. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015121239-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015121241-A1 |
priorityDate | 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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