http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2657334-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fcb09d561162847dcb226388ebf67d9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate | 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e2ebc560b60085898c72bc4393dbbc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a05c0c3059af935f5e63f93553b3b94a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_857a24e827bb31e912eafd3f9551d56b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bf8434b642d9348fc85f399d5dd02ed |
| publicationDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2657334-A1 |
| titleOfInvention | Efficient method for displaying protein multimer |
| abstract | The present invention provides a method of producing a protein multimer-nucleic acid complex comprising a protein multimer and any one target component of the protein multimer, which comprises the following steps: ni) translating a nucleic acid encoding the target component into the target component by an in vitro translation system to give a translation product containing a target component-nucleic acid complex containing the target component and the nucleic acid encoding the target component, and nii) translating a nucleic acid encoding a non-target component constituting the protein multimer together with the target component into the non-target component by adding the nucleic acid encoding the non-target component to the translation product obtained in i) to give the non-target component, associating the non-target component with the target component contained in the target component-nucleic acid complex to form a protein multimer, thus affording the protein multimer-nucleic acid complex comprising the protein multimer and the nucleic acid encoding the target component. n By performing in vitro selection such as ribosome display, mRNA display and the like using the present invention, the function such as binding affinity and the like of a complicated protein multimer such as antibody and the like can be increased or improved efficiently. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2989239-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10731148-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114199875-A |
| priorityDate | 2012-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.