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filingDate 2013-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09260868c52ec9509bdb362689c8586c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_600c3325cf6f84134431d08fb41a219d
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publicationDate 2013-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2644608-A1
titleOfInvention One-pot process for the synthesis of iloperidone
abstract Disclosed is a process for the synthesis of iloperidone starting from 4-hydroxy-3-methoxy acetophenone (acetovanillone), 1-chloro-3-bromo propane and 6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride, using a one-pot method.n n Said process is performed without any intermediate isolation, and is particularly advantageous from the environmental standpoint and in terms of yields, productivity and the purity of the product obtained, both in the reaction mixture and in the crystal isolated.
priorityDate 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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