abstract |
Provided herein are (8 S , 9 R )-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-lH-1,2,4-triazol-5- yl)-8,9-dihydro-2 H -pyrido[4,3,2- de ]phthalazin-3(7 H )-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8 S ,9 R )-5-fiuoro-8-(4-fluorophenyl)-9-(1-methyl-1 H -1,2,4-triazol-5-yl)-8,9-dihydro-2 H - pyrido[4,3,2- de ]phthalazin-3(7 H )-one tosylate salt are also provided, as are methods of using (8 S ,9 R )-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1 H -1,2,4-triazol-5-yl)-8,9-dihydro-2 H - pyrido[4,3,2- de ]phthalazin-3(7 H )-one tosylate salt to treat a disease or condition, such as a cancer. |