http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2625187-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e8b371a214bb63566d341ab1b0b80cd |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2011-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e9363c53283a92ec31a4985264297e6 |
publicationDate | 2013-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2625187-A1 |
titleOfInvention | Phosphoramidite derivatives of gemcitabine for use in the treatment cancer |
abstract | Phosphorodiamidate derivatives of e.g. gemcitabine are provided for use in treating cancer. In one embodiment, the two amidate motifs each comprises NR'R" where R' is H and R" is CR 5 R 6 CO 2 R 7 , where R 6 is H, R 5 is the side chain, including H and C 1, of a naturally occuuring alpha amino acid, and R 7 is branched or unbranched, substituted or unsubstiruted, acyclic or cyclic alkyl, including t -butyl-CH 2 -, benzyl and C 3 to C 6 cycloalkyl.Formula (I). |
priorityDate | 2010-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.