| abstract |
The Present invention provides a useful morpholino nucleic acid derivative for synthesizing a morpholino nucleic acid oligomer. nThe present invention provides a compound represented by the following general formula (1) or a salt.n nwherein R 1 represents hydrogen, trityl and so on. nR 2 represents amide or imine. nR 3 represents a hydroxy group which may be protected by trialkylsilyl and so on, or a group represented by the following general formula (5).n n(wherein X represents O or S. Y represents dialkylamino or alkoxy. Z represents chlorine.) |