Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64fab711e94aa910dfb7511bb1bf834e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C31-202 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-69 |
filingDate |
2011-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ae89276e7376ed9e3bec7bf1b8b6c6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f252aff1bbf44d64787977faeb891b1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e8f625c57d9082c74df1a3cbc28a729 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df67926b720959790aee6814bb01ffb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a77d8e7ba491da135be047b207caf89d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f80f4a9b7b006f8ce573861983ff5594 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1e155d192dac1cad21e92098762dbf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dee90a9627c679cdd02be4cd52996a8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_128cd4d122a6e96c4e5a04965d8f27e7 |
publicationDate |
2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2621909-A1 |
titleOfInvention |
Process for preparing bosentan monohydrate and its intermediates |
abstract |
The present invention relates to a process for preparing Bosentan Monohydrate; in particular, the present invention provides the preparation of the novel 4-tert- butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-pyrimidinyl)- pyrimidin-4-yl]-benzenesulfonamide sodium salt as an ethylene glycol solvate (Bosentan sodium salt ethylene glycol solvate), which is a useful intermediate for obtaining Bosentan Monohydrate in a pure form. |
priorityDate |
2010-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |