abstract |
Compounds of formula I or a pharmaceutically acceptable salt, solvate, hydrate or derivative thereof wherein R 1 is halogen or halo-C 1 -C 6 -alkyl; R 2 is a group of formula II or III; R 3 is halogen, and n is 1 or 2, inhibit nuclear export of antiviral and tumor-suppressing cellular factors and are useful in the treatment or prophylaxis of cancer or viral diseases. |