http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2601945-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7711b7587368f45c366ad1c4743da017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9cd05647a7ddd6cf5820ca8b9de6d6d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-16 |
| filingDate | 2011-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7689c1788015b07b8be68ad3a64b15f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f72456051edbab70dfe454f188e7f88 |
| publicationDate | 2013-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2601945-A1 |
| titleOfInvention | Inhibition of cis-platin induced ototoxicity |
| abstract | The invention describes diphenylhydramine (DPH) for treating ototoxicity in a subject, for inhibiting the formation of platinum adducts in a cell of the inner ear, and for preventing and/or inhibiting structural and functional damage in the inner ear. Furthermore, the invention describes an in vitro method for determining a subject's susceptibility for platinum induced ototoxicity and/or platinum induced nephrotoxicity and an in vitro method for screening a compound for inhibiting ototoxicity induced by a platinum complex as well as a kit useful for screening. The invention also describes a composition for treating cancer and concurrently inhibiting ototoxicity, nephrotoxicity and/or neurotoxicity. The invention further describes DPH for treating nephrotoxicity in a subject induced by a medication comprising a platinum complex. |
| priorityDate | 2011-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 176.