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filingDate 2011-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7be24fc0a80719e3818712489c2d8869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42b09bb36bb8721b6ec004443f39e913
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0766077ec0dad8f70239a38b6eb374e3
publicationDate 2013-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2601525-A1
titleOfInvention Use of hmgb1 as a biological marker of bowel inflammatory conditions, non-invasive method for its detection in fecal samples and kit thereof
abstract A non-invasive method for measuring a bowel inflammatory condition in humans through the presence of HMGB1 protein in fecal extracts and the involvement of such protein in the pathogenesis of chronic inflammatory bowel diseases, more specifically of Crohn's Disease (CD) and of ulcerative colitis (UC), comprising an analysis protocol to detect the HMGB1 presence in feces through Western blot assay or ELISA assay using an appropriate antigen-antibody. The invention also comprises the colorimetric kit for implementing such a method.
priorityDate 2010-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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