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filingDate 2011-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df7b73faa5a43ab2fc646af5cf9f2832
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publicationDate 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2588491-A2
titleOfInvention Novel peptide and use thereof
abstract The present invention provides a peptide represented by formula (I) of X 1 -Leu-X 2 -Leu-X 3 wherein X 1 represents Glu or Asp, X 2 represents His, Lys or Arg, X 3 represents Asp or Glu, with Glu, Asp, Leu, His, Lys and Arg being respectively glutamic acid, aspartic acid, leucine, histidine, lysine and arginine; or a pharmaceutically acceptable salt thereof; a composition for the treatment or prevention of at least one selected from cartilage damage and arthritis, containing the same peptide or a pharmaceutically acceptable salt thereof as an active ingredient; and a composition containing the same peptide or a pharmaceutically acceptable salt thereof and TGFβ1. The above-mentioned peptide or a pharmaceutically acceptable salt thereof is effective for the treatment and/or prevention of cartilage damage and/or arthritis and is capable of exhibiting effects of the regeneration of cartilage tissue, the inhibition of the expression of cartilage tissue matrix degrading enzyme and/or the inhibition of cartilage tissue ossification.
priorityDate 2010-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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