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filingDate 2010-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d01887f327a753331cc344ce7fa13e36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18f4a65e8df35e14affb202b3daeb4bf
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publicationDate 2013-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2576813-A1
titleOfInvention Procedure for biphasic preparation of liposomes and application thereof in manufacturing diagnostic reagents
abstract The invention relates to a procedure for biphasic preparation of liposomes, in the course of which technically simple and cheap mechanical mixing methods are used to commingle non-polar organic phase containing an individual mixture of natural and synthetic phospholipids and polar aqueous (buffer) phase not miscible with it, resulting in a liposome emulsion of a unique structure. Furthermore, the invention comprises embodiments of the procedure related to the in vitro diagnostic use of liposomes prepared in this way, when protein type active components are anchored to the surface of liposome membranes without application of any detergents and non-protein type active components are simply mixed with the liposome emulsion of a unique structure. In one of the possible embodiments of the procedure a Prothrombin Time (PT) reagent is prepared. Another possible embodiment of the procedure is the preparation of an activated partial thromboplastin time (APTT) reagent.
priorityDate 2010-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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