Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10bd7baf82e51a4b37e0e24ee06d11ef |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-80 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 |
filingDate |
2011-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0858259666e0e0c4e0af3cdcfee7381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_623d24116617e50bf81810258b7a2532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15b0161793f2d3a12e27abc4ff9b9823 |
publicationDate |
2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2573173-A1 |
titleOfInvention |
Chimeric nucleases for gene targeting |
abstract |
The invention describes chimeric nucleases consisting of a DNA binding site derived from a TALE protein, a linker, and a cleavage module derived from a restriction endonuclease which are used for gene targeting efforts. The chimeric nucleases according to the invention exhibit increased preference and specificity to bipartite or tripartite DNA target sites comprising TALE recognition site(s) and restriction endonuclease target site while cleaving at off-target sites comprising only the restriction endonuclease target site is prevented. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014207246-A1 |
priorityDate |
2011-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |