http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2571999-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2011-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b99c5e6f09d783d94a854236e894659 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce0e8de2ae70ed8ab384090428be87ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19e3dc41861fa97fad6f6da0715d4e46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ba15b1647bd2b1a94cda95b7c3e2d2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48b6fd94b50ac0811f9569d750999210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93cb119955aee57e4fd9568ba1dccef6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d8bc8480a0d5fe634827564eeacba3c |
| publicationDate | 2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2571999-A2 |
| titleOfInvention | System and method for tailoring nucleotide concentration to enzymatic efficiencies in dna sequencing technologies |
| abstract | An embodiment of a method for optimizing sequencing performance is described that comprises the steps of calculating a nucleotide species specific degradation rate of an apyrase enzyme for a plurality of nucleotide species; determining a concentration for each of the nucleotide species using the nucleotide species specific degradation rate; iteratively providing the concentration of each of the nucleotide species in a reaction environment comprising a polymerase enzyme and a species of template nucleic acid molecule, wherein one or more molecules of the nucleotide species are incorporated into a nascent molecule in a sequencing reaction and the apyrase enzyme is introduced to the reaction environment to degrade unincorporated nucleotide species molecules; and detecting a signal in response to the incorporation of the nucleotide species. |
| priorityDate | 2010-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.