| abstract |
The present invention relates to the preparation of highly efficient chiral heterogeneous catalyst for asymmetric nitroaldol reaction, wherein Henry reactions of various aldehydes such as aromatic, aliphatic, α,β-unsaturated aldehydes, alicyclic aldehydes and nitroalkenes were carried out to produce optically active β- nitroalcohols in high yield, with moderate to excellent enantioselectivity (ee up to >99 %) in presence of a base and an optically active chiral heterogeneous catalyst. |