Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a431f1e5f5bd51f2842c97425b320542 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 |
filingDate |
2011-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3025d32a84e252835ab46f6f89027efb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c051fe245a9518d95885f127ed4f3fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98dbb706ca6ac5e1ef54c51373b39ebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5175527435d6de77fdf7a4b8193e7ca0 |
publicationDate |
2013-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2544677-A2 |
titleOfInvention |
Beta -adrenergic receptor agonists and uses thereof |
abstract |
Provided herein are methods for improving function in a retinal cell associated with a diabetic condition and for treating a diabetic retinopathic condition in a subject. The methods comprise contacting the retinal cell or administering to the subject a beta-adrenergic receptor agonist such as have the chemical structural formula (I): where R 1 is (CH 2 ) n (CH 3 ) 2 or formula (II) where n is 1 to 4, R 2 is H or H⋅HX, where X is a halide and R 3 is O(CH 2 ) m CH 3 at one or more of C2-C6, where m is 0 to 4. Also provided are BAR agonists having the structural where R 1 is the (CH 2 ) n -phenyl-R 2 substituent and the hydroxy-benzene moiety is 1,2- benzene diol or 1,3-benzene diol. |
priorityDate |
2010-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |