Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a80a136273e54c4408e5cb9f8e85509a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58f2b3ea12a3b44e938074d7af711618 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-231 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0635 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0781 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
filingDate |
2006-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3731cb0ce8b4ffe9b6c2d33da962708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed3ffe3377e379a4d13c445554a52264 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_307b458980dd9fa15d52518087f3ee76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c94c03383984acc12f03bfa288980489 |
publicationDate |
2013-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2540820-A1 |
titleOfInvention |
Means and methods for influencing the stability of antibody producing cells |
abstract |
The invention provides methods for increasing the replicative life span and/or stability of an antibody producing cell, comprising n- providing said antibody producing cell with a compound capable of directly or indirectly enhancing BCL6 expression and/or culturing said antibody producing cell in the presence of a compound capable of directly or indirectly enhancing BCL6 expression; and n- directly or indirectly increasing the amount of Bcl-xL or another anti-apoptotic gene expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016201077-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11125757-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124766-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3307070-A4 |
priorityDate |
2005-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |