http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2529734-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24ce2ecfefe8e997ca7a1fb6f98bafc9 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C203-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-27 |
filingDate | 2012-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97c97db00ef16b5584f0ac43f53e64cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d2ed22f98c2845a058e06e62ee5e60d |
publicationDate | 2012-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2529734-A1 |
titleOfInvention | Nitrate esters and their use for the treatment of muscle and muscle related diseases |
abstract | Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula:n nwherein, nR 1 is ONO 2 , CH 2 ONO 2 , C n H 2n+1 OH, C n H 2n+1 OH, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , or H; nR 2 is ON0 2 , CH 2 ONO 2 , C n' H 2n'+1 OH, C n' H 2n'+1 OH, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , or H; nR 3 is ON0 2 , CH 2 ONO 2 , C n" H 2n"+1 OH, C n" H 2n"+1 OH, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , or H; and nR 4 is ON0 2 , CH 2 ONO 2 , C n" H 2n"+1 OH, C n" H 2n"+1 OH, CH 3 , CH 2 CH 3 , CH 2 CH 2 CH 3 , or H; wherein n is an integer from 0 to 9, n' is an integer from 0 to 9, and n" is an integer from 0 to 9, and n+n'+n" ≤ 9, and wherein at least one of R 1 , R 2 , and R 3 is an ester nitrate selected from the group consisting of ON0 2 , CH 2 ONO 2 , and combinations thereof. |
priorityDate | 2011-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 327.