| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b6121dedd894b3f760906b68697d616 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_634f490d3df44dd81edf1917f4d10f86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bea16d7d5d58bd34765e558563ccd2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab43707fe1d6f721072bcd360e1116c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24370dac346abc762258b1ae7b0416d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1e95a4d28e8e2cca9782a321decc003 |
| publicationDate |
2013-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2527460-A9 |
| titleOfInvention |
Methods for prediction of clinical outcome to epidermal growth factor receptor inhibitors by cancer patients |
| abstract |
The present invention relates to a method to obtain an expression score to evaluate gene expression in a tissue specimen obtained from a person having or suspected of having cancer comprising: na) determining by immunohistochemistry a fraction score, wherein the fraction score corresponds to the percentage of cells in the tissue specimen that stain positive for a biomarker; nb) determining an intensity score that corresponds to the staining intensity of the biomarker in the sample of tumor cells; nc) calculating an expression score that is a numerical evaluation of the product of the fraction score and the intensity score. |
| priorityDate |
2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |