http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2522352-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
filingDate | 2006-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8235fa78d71d22758f8e86b6a99b0c0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fd9f8a77049bb08805ecd8ed0ea276d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f367981b577e60774e797a3b704325e |
publicationDate | 2012-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2522352-A1 |
titleOfInvention | Methods for cancer therapy and stem cell modulation |
abstract | The present invention relates to a method of modulating pluripotency and/or self-renewing characteristics of a stem/progenitor cell. The method comprises administering to the respective cell a compound of the general formula (I)n n In the general formula A is C or N. R 1 , R 4 and R 5 are, independently selected, H or aliphatic, cycloaliphatic, aromatic, arylaliphatic, or arylcycloaliphatic hydrocarbyl groups, that comprise 0 - 3 heteroatoms being N, O, S, or Si. R 4 and R 5 may optionally be linked so as to define an aliphatic hydrocarbyl bridge. R 2 is H or a halogen, such as F or Cl. R 3 is H, or an aliphatic or arylaliphatic hydrocarbyl group comprising 1 - 8 main chain carbon atoms and 0 - 3 heteroatoms being N, O, S, Si, or a halogen such as Cl or F. Also provided is a method for modulating gene expression in a cell that expresses the components of a polycomb repressive complex. |
priorityDate | 2006-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1507.