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filingDate 2010-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9edb48cd4f8daf7e99377473f3cb905
publicationDate 2012-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2514768-A1
titleOfInvention Fusion polypeptide against eb virus-induced tumor and colicin ia mutant
abstract The present invention provides a fusion polypeptide against EB virus-induced tumor, which comprises an antibody or a mimetic antibody against EB virus and an ion channel forming colicin selected form E1. Ia, Ib, A, B, N and their mutants. The present invention also provides a colicin Ia mutant, which comprises mutations of G11A, H22G, A26G, V31L, and H40D. The present invention also provides a gene, vector, preparation method and use of the fusion polypeptide, and provides a gene and use of the mutant.
priorityDate 2009-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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