http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2514434-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51a0c49e5390c69aa92b87c3a892344c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2007-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0678188411a96ad1fc085f7fa5d3f9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfa3273861339755fefdbc8eef9c4ebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6afc23dbf9a2d3d95ea0c3a430fae00c |
| publicationDate | 2012-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2514434-A2 |
| titleOfInvention | MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer |
| abstract | The invention provides methods of diagnosing whether a subject has, or is at risk for developing, lung cancer, comprising measuring the level of at least one miR gene product in a test sample from said subject, wherein an alteration in the level of the miR gene products in the test sample, relative to the level of corresponding miR gene products in a control sample, is indicative of the subject either having, or being at risk for developing, lung cancer. n The invention also provides methods of diagnosing whether a subject has, or is at risk for developing, lung cancer, comprising: nreverse transcribing RNA from a test sample obtained from the subject to provide a set of target oligodeoxynucleotides; nhybridizing the target oligodeoxynucleotides to a microarray comprising miRNA-specific probe oligonucleotides to provide a hybridization profile for the test sample; and ncomparing the test sample hybridization profile to a hybridization profile generated from a control sample, nwherein an alteration in the signal of at least one miRNA is indicative of the subject either having, or being at risk for developing, lung cancer. n The at least one miR gene product is selected from the group consisting of miR-21, miR-191, miR-155, miR-210, miR-126* and miR-224. |
| priorityDate | 2006-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 460.