http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2511382-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4f8755c361b70eb6af66fd6a114e590 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f28e56d90dc7f9053ba6aa541cb52d38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a7f3bde5d03e41f43bfffc1a550d0ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_348daaf4f39c6ea17a142e2a2923c732 |
| publicationDate | 2012-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2511382-A1 |
| titleOfInvention | Process for identifying novel anti-inflammatory molecules with reduced direct transrepression of genes induced by glucocorticoids |
| abstract | The present invention relates to a new process for identifying novel anti-inflammatory molecules with reduced direct transrepression of genes induced by glucocorticoids. n The inventors have discovered that GCs-mediated transrepression can be mediated not only via the tethering indirect pathway, but also through direct binding of GR to "simple" negative GREs (nGRE), which belongs to a novel family of evolutionary-conserved cis-acting negative response elements (IR nGREs), and are found in numerous GC-repressed genes. |
| priorityDate | 2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1168.