http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2508525-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f52c68e4149a6c462b850d4e7cc2b2f9 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate | 2011-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf81780449a134cb08ae03930c93624 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14c75914ca623bfac96b014ef8b0a4fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aec867e2785ce7efcb180602af8a261 |
publicationDate | 2012-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2508525-A1 |
titleOfInvention | Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts |
abstract | The present invention relates : n- to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II) :n nor a tautomer, solvate or hydrate thereof ; n- to methods of preparing said dihydrochloride salt ; n- to said dihydrochloride salt for the treatment and/or prophylaxis of a disease; n- to the use of said dihydrochloride salt for the preparation of a medicament for the treatment and/or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, more particularly for the treatment or prophylaxis of a cancer, particularly lung cancer, in particular non-small cell lung carcinoma, colorectal cancer, melanoma, pancreatic cancer, hepatocyte carcinoma, pancreatic cancer, hepatocyte carcinoma or breast cancer ; n- to a pharmaceutical composition comprising said dihydrochloride salt ; and n- to a pharmaceutical combination comprising said dihydrochloride salt in combination with one or more further pharmaceutical agents. |
priorityDate | 2011-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1417.