| abstract |
A conformable barrier sheet comprising a polymeric film having a tensile elongation at least 2 fold greater than a polyethylene terephthalate film of equal dimensions and under an equal load; a planarization layer; and a plasma-deposited amorphous glass layer comprising silicon, carbon, and hydrogen; wherein the planarization layer is disposed on the polymeric film, the amorphous glass layer is deposited on the planarization layer, and wherein the barrier sheet is sufficiently conformable that after undergoing a tensile elongation within the range of more than 2 % to 20 %, the barrier sheet has a moisture vapor transmission rate essentially unchanged compared with prior to being elongated, a method of making the conformable barrier sheet, a transdermal device comprising the conformable barrier sheet, a method of delivering a drug to a mammal using the device, and a method of protecting an article using the conformable barrier sheet are provided. |