http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2500426-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y113-12007
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
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filingDate 2010-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05000bf6a24578c3121f6d558d8123ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9187dec78e77f5ea0ee268cd07455212
publicationDate 2012-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2500426-A1
titleOfInvention Firefly luciferase and gene thereof, and process for production of firefly luciferase
abstract There are provided, firefly luciferase with excellent thermostability and/or storage stability and a process for its production. n Firefly luciferase having the amino acid sequence of firefly luciferase, wherein the amino acid corresponding to position 287 of Heike firefly luciferase has been replaced with alanine, or wherein the amino acid corresponding to position 392 has been replaced with isoleucine, and a gene for the firefly luciferase. n By utilizing this gene, it is possible to efficiently produce firefly luciferase with increased stability. It is also possible to obtain firefly luciferase with further increased stability by combination with a mutation in which the amino acid at position 326 has been replaced with serine, and/or a mutation in which the amino acid at position 467 has been replaced with isoleucine.
priorityDate 2009-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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