| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12fcc57f00b125c60e882f07ea8d4673 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y107-03003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0048 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06 |
| filingDate |
2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b76b8f8eb0bb08451d3441705164682f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d72a5bdfb508876bfbb6487e56ed699e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f350d129e05e8712114b7e58e0ef63fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46987f6876fa2774b9d33202d6ed7c80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e75a0c2243a60c525a1a328229c8689 |
| publicationDate |
2012-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2495315-A1 |
| titleOfInvention |
Humanized recombinant uricase and mutants thereof |
| abstract |
The present invention provides a humanized recombinant uricase and mutants thereof, wherein the humanized recombinant uricase is a chimeric protein which comprises amino acids of non-human mammal uricase and amino acids of human uricase. The humanized recombinant uricase and mutants thereof have reduced immunogenicity in human, and can be used for the treatment of hyperuricemia and gout. |
| priorityDate |
2009-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |