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filingDate 2012-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2012-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2487489-A1
titleOfInvention Novel method for testing vascular endothelial damage and testing kit
abstract An object of the present invention is to provide a method which is capable of carrying out detection and evaluation of the vascular endothelial damage with a high degree of accuracy. According to an aspect of the present invention, there is provided a method for testing vascular endothelial damage with respect to a blood sample collected from living organism comprising the steps of: 1) detecting or determining quantitatively vascular endothelial cell-derived microparticle; and 2) detecting or determining quantitatively tissue factor-containing microparticle. Furthermore, according to another aspect of the present invention, there is provided a testing kit of vascular endothelial damage comprising a first antibody which specifically recognizes the vascular endothelium-derived microparticle, and a second antibody which specifically recognizes the tissue factor-containing microparticle.
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