http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2486791-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_083f591ef795609c898634d3ee80a724 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8258 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H1-00 |
| filingDate | 2010-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a36c36439e4027d705903e0c5a1016f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04bca0b4a22b9faec780df3f0de747ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5f9f07ab2353aebb86894642a15c830 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_053acfe05a1a5a9490cbf9aa157539e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e372b7cca1ea1d5dbc9cb67b986ad3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48a7c8797ac637158f270d338c9a9d79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46e8b574fb4b7b286d72af30882fae59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7695af54e6879ad2c5606d64ece2a7bf |
| publicationDate | 2012-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2486791-A2 |
| titleOfInvention | Highly pathogenic avian influenza virus protein vaccine derived from transgenic plants, and method for preparing same |
| abstract | The present invention relates to a method for producing transgenic plants, which involves producing hemagglutinin proteins of the H5N1 virus in a highly efficient manner using a plant transformation recombinant vector, wherein said vector can express, in a highly efficient manner, hemagglutinin proteins of the H5N1 virus which is the highly pathogenic avian influenza virus, and can transport proteins expressed in plants to the endoplasmic reticulum and enable the retention of the proteins in the endoplasmic reticulum so as to accomplish glycosylation which is necessarily required for antigen activity. The present invention also relates to a method for the mass production of hemagglutinin proteins of the antigenic H5N1 virus from the transgenic plants, and to a vaccine composition for the avian influenza virus comprising the transgenic plants or the hemagglutinin proteins produced from the plants. The method for producing hemagglutinin proteins of the H5N1 virus using transgenic plants according to the present invention enables the mass production of hemagglutinin proteins at a low cost. The plant transformation recombinant vector used in the present invention has a cellulose-binding domain inserted therein to separate proteins expressed in plants in a quick and easy manner. In addition, transgenic plants according to the present invention can be taken in the form of feed additives or the like, and therefore can be used as edible vaccines. Further, antigenic hemagglutinin proteins produced by the method induce immune response when administered to an animal model, and therefore can be used not only as protein vaccines for the H5N1 avian influenza virus, but also as diagnostic reagents for avian influenza virus infection. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020079656-A1 |
| priorityDate | 2009-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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