| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2535-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2535-131 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate |
2008-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e164a8589e63b169ee4db73cf798d0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd70e2f65bc67f487c9fee8ec11e7bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eafb6b743e43487368e4de1831453b56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43cb4b6622a37723e5bc8303114d0a97 |
| publicationDate |
2012-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2481807-A2 |
| titleOfInvention |
In vivo HCV resistance to anti-viral inhibitors |
| abstract |
HCV mutations emerged in chimpanzees treated with a N5B polymerase inhibitor (Compound A) or a NS3 protease inhibitor (Compound B). Short term treatment with Compound A was followed by the initial emergence of an HCV with a S282T polymerase mutation following treatment. Short term treatment with Compound B selected for HCV with a R155K or D168T protease mutation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104530189-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104530189-A |
| priorityDate |
2007-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |