| abstract |
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a plurality of assays, one or more of which is configured to detect a kidney injury marker selected from the group consisting of metalloproteinase inhibitor 2, soluble oxidized low- density lipoprotein receptor 1, interleukin-2, von Willebrand factor, granulocyte- macrophage colony- stimulating factor, tumor necrosis factor receptor superfamily member HB, neutrophil elastase, interleukin- 1 beta, heart- type fatty acid-binding protein, beta-2-glycoprotein 1, soluble CD40 ligand, coagulation factor VII, C-C motif chemokine 2, IgM, CA 19-9, IL-IO, TNF-α, and myoglobin as diagnostic and prognostic biomarkers in renal injuries. |