| abstract |
The present invention provides (poly)peptides, which are recognized by human cytomegalovirus (CMV)-specific immune cells. The present invention further provides a combination of multiple CMV (poly)peptides, comprising at least two different groups of (poly)peptides according to the invention as well as conjugates, comprising said (poly)peptides and/or immune adjuvants thereof. Furthermore, this invention provides mixtures, comprising said (poly)peptides and/or immune cells (20) thereof, which are used to generate CMV-specific immune effector cells (31) with high sensitivity and specificity. In addition, the present invention provides a preparation method of CMV-specific immune effector cells (31), by using said (poly)peptides, adjuvants, immune cells (20) and/or mixtures thereof to generate anti-CMV immune response. |