http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2459543-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c3f1f33dfbb934e77dbfc6024264aa6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2010-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7684ef83d6a67bf37bda261f397c430a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb3c53b83a0ce9f8d835fef5f6b47cf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6088ec79fcd2c354332491f7bb2dfdd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64f4ab8a2725f040ab6f4a183e6e9c79 |
| publicationDate | 2012-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2459543-A1 |
| titleOfInvention | Benzo [e][1, 3]oxazin-4-one derivatives as phosphoinositide 3-kinase inhibitors |
| abstract | Compounds of formula (I): wherein: W is O, N-H, N-alky!, N-alkenyl, N-alkynyl, N-aryl, N-heteroaryl or S; each X is independently CH or N; R 1 is formula (b) or R 3 is H, alkyl, NH 2 , OH, =0 or halogen; each A and B are independently CH or N; D is NHR 4 ; R 4 is H, alkyl, -C(O)- alkyl. -C(O)-NH 2 , -C(O)-NH- alkyl, -SO 2 - alky!, -SO 2 -NH 2 or -SO 2 -NH- alkyl; R 2 is aryl substituted with at least one nitrogen-containing group or R 2 is a nitrogen-containing heteroaryl, cycloalkyl substituted with a nitrogen-containing group, nitrogen-containing cycloalkyl, C 1 -C 6 mono alkylamino, C 1 C 6 bis alkylamino, C 1 C 6 acylamino, C 1 -C 6 aminoalkyl, mono (C 1 C 6 alkyl) amino C 1 -C 6 alkyl, bis (C 1 C 6 alkyl) amino C 1 C 6 alkyl, C 1 -C 6 -acylamino or C 1 C 6 alkynyl-NR 11 ; R 11 is H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, halogen, O-alkyl, NH-alkyl, N-dialkyl, -C(O)-R 7 , -C(O)-NH 2 , -C(O)-NH-R 7 , -SO 2 -R 7 , -SO 2 -NH 2 , -SO 2 -NH- R 7 , NH-acyl, NH-sulfonyl, NR 7 -acyl, NR 7 -suIfonyl, N-C(O)-NH-R 7 , N-SO 2 -NH-R 7 , N-C(O)-NR 7 R 7 or N-SO 2 -NR 7 R 7 ; and R 7 is alkyl, aryl or heteroaryl, are useful as PI3K inhibitors and are useful in therapy. |
| priorityDate | 2009-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.