http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2453237-A1
Outgoing Links
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|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5808a0f30c29a7f59367bb575049cd75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc8afb712001d187c77234766d512720 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6441 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6419 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-367 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-36 |
| filingDate | 2006-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e898543d0ec490fa4627ddf2ee1a3f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02758352c69cc818eba6d47cfb7af653 |
| publicationDate | 2012-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2453237-A1 |
| titleOfInvention | Optical microscopy with phototransformable optical labels |
| abstract | First activation radiation is provided to a sample (601) that includes phototransformable optical labels ("PTOLs") to activate a first subset of the PTOLs in the sample (601). First excitation radiation is provided to the first subset of PTOLs in the sample (601) to excite at least some of the activated PTOLs, and radiation emitted from activated and excited PTOLs within the first subset of PTOLs is detecting with imaging optics (602). The first activation radiation is controlled such that the mean volume per activated PTOLs in the first subset is greater than or approximately equal to a diffraction-limited resolution volume ("DLRV") of the imaging optics (602). nThe sample (601) comprises at least a first species and a second species of PTOL, which are distinguished from each other based on at least one of emission characteristics of the first and second species and excitation characteristics of the first and second species. A density of each species of PTOL in the sample is greater than the inverse of DLRV of the imaging optics, and a density of species of PTOL in the first subset of activated PTOLs of that species is less than the inverse of the diffraction-limited resolution volume. The PTOLs may be formed by photoactivated or photoswitched fluorescent proteins. The method and the apparatus allow to obtain superresolution images. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107003241-A |
| priorityDate | 2005-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.